The Brazilian government has issued a permit for testing on Thursday.
The vaccine is made by the University of Oxford, UK.
The vaccine is the only way to pave the way for the fight against the virus, the National Health Watch (Anvisa) said.
And Brazil will be the first country outside of the UK to receive the vaccine.
The test will be conducted with the full support of the Brazilian health minister and will be used only for patients
Never had a virus like this before and it was voluntary.
The vaccine has already been tested in labs using chimpanzees and is now starting to be tested in humans.
10,000 in the UK and will continue to test overseas, Brazil, to make the level more clear.
Edit: Sun Lee